Restarting Anticoagulant Therapy After Intracranial Hemorrhage

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Restarting Anticoagulant Therapy After Intracranial Hemorrhage

Atrial fibrillation increases the risk of stroke 3to 5-fold and is implicated in about 15% of all strokes every year. Anticoagulation therapy has been proven to be efficacious in reducing incident stroke and systemic embolism in patients with atrial fibrillation and mechanical heart valves. However, the benefits of anticoagulation must be carefully weighed against the increased risk of intracra...

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Restarting oral anticoagulation after intracranial hemorrhage.

To the Editor: In their recent article, Eckman and colleagues highlight a difficult clinical decision: whether it is safe to restart anticoagulation for atrial fibrillation after intracerebral hemorrhage, and they cite the lack of published data addressing the issue.1 We agree that decisions must be made based on the relative risks versus benefits in individual patients, which will vary dependi...

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Restarting Anticoagulant Treatment After Intracranial Hemorrhage in Patients With Atrial Fibrillation and the Impact on Recurrent Stroke, Mortality, and Bleeding

Patients with AF who survive an ICH are at an increased risk of subsequent ischemic stroke. Thus, a major unanswered question is the efficacy and safety of restarting OAC treatment, relative to not restarting OAC, following a presentation with ICH. Patients with prevalent ICH were excluded from randomized clinical trials of OAC for stroke prevention, and only small case control or cohort studie...

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Anticoagulant Therapy-Induced Gallbladder Hemorrhage after Cardiac Valve Replacement

Anticoagulation therapy is essential after cardiac valve surgery. However, spontaneous bleeding remains a major concern during anticoagulation therapy. Spontaneous gallbladder (GB) hemorrhage (hemobilia) is a rare occurrence during standard anticoagulation therapy. This report presents a case of GB hemorrhage that occurred shortly after initiating oral anticoagulant therapy in a patient who had...

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Restarting Anticoagulant Treatment After Intracranial Hemorrhage in Patients With Atrial Fibrillation and the Impact on Recurrent Stroke, Mortality, and Bleeding: A Nationwide Cohort Study.

BACKGROUND Intracranial hemorrhage is the most feared complication of oral anticoagulant treatment. The optimal treatment option for patients with atrial fibrillation who survive an intracranial hemorrhage remains unknown. We hypothesized that restarting oral anticoagulant treatment was associated with a lower risk of stroke and mortality in comparison with not restarting. METHODS AND RESULTS...

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ژورنال

عنوان ژورنال: Stroke

سال: 2017

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.116.016327